How Psilocybin Rewires the Brain: The Science of Neuroplasticity TL;DR: Psilocybin promotes neuroplasticity by activating the brain’s 5-HT2A serotonin receptors, triggering BDNF and mTOR signalling pathways that stimulate dendritic spine growth, neurogenesis, and new synaptic connections. Preclinical and clinical research suggests these brain changes may underpin psilocybin’s therapeutic effects on depression, PTSD, and anxiety — […]
Tag Archives: psilocybin Canada
The History of Magic Mushroom Use Around the World TL;DR: Magic mushrooms have been used by humans for at least 9,000 years, with evidence spanning Africa, Mesoamerica, Europe, and Asia. Revered in ancient spiritual ceremonies and rediscovered by Western science in the mid-20th century, psilocybin is now the subject of serious clinical research. In Canada, […]


